Evidence map›Paper›PMID 42519463›Full record

ArticlePhotoacoustics2026

Quantitative assessment of gastrointestinal motility in neonatal rats by real-time 3D photoacoustic imaging: A feasibility study.

Tingting Huang, Li Li, Yu Sun, Yibing Wang, Xinlin Hou, Changhui Li

Abstract read
In one paragraph

Article in Photoacoustics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tingting HuangCollege of Future Technology, Peking University, Beijing, China.
Li LiThe Children's Medical Center, Peking University First Hospital, Beijing, China.
Yu SunCollege of Future Technology, Peking University, Beijing, China.
Yibing WangCollege of Future Technology, Peking University, Beijing, China.
Xinlin HouThe Children's Medical Center, Peking University First Hospital, Beijing, China.
Changhui LiCollege of Future Technology, Peking University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal (GI) motility assessment in neonates remains challenging for conventional clinical imaging. We present a preliminary quantitative framework for GI dynamics in healthy neonatal rats using a real-time three-dimensional photoacoustic imaging system, enabling high-contrast visualization of gastric and intestinal structures. India ink was administered orally as a contrast agent to enhance visualization of the GI tract. We developed a dual-branch analysis pipeline including spatiotemporal kymography for local rhythmic activity quantification and cluster tracking for transport-pattern classification. In healthy neonatal rats, intestinal rhythmic activity was measured at 9.25 ± 0.96 cycles per minute, while gastric peristaltic waves were identified from kymographs. Tracking of contrast-agent clusters revealed local propulsive and retrograde transport patterns, while segmental-like activity was identified from cluster-splitting events. This feasibility study demonstrates a volumetric GI imaging and analysis method for neonatal GI kinematics, laying a foundation for future larger-scale validation and disease-model studies.

Indexed as

3D dynamic imagingGastrointestinal imagingIntestinal motilityPhotoacoustic imaging

Identifiers

PMID42519463
PMCPMC13382320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.