Evidence map›Paper›PMID 42519390›Full record

ArticleMolecular therapy. Oncology2026

Lnk Governs chemokine-directed trafficking of CD8

Yael Derdikman Ofir, Miran Aswad, Michal Hayun, Antonina Pechkovsky, Ghazal Kheshaiboun, Narmeen Ghanayiem, Yasmine Khier, Yaniv Zohar, Yishai Ofran, Igal Louria-Hayon

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yael Derdikman OfirSection of Medical Oncology, Yale School of Medicine, New Haven, CT 06510, USA.
Miran AswadThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.
Michal HayunThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.
Antonina PechkovskyThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.
Ghazal KheshaibounThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.
Narmeen GhanayiemThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.
Yasmine KhierThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.
Yaniv ZoharDepartment of Pathology, Rambam Health Care Campus, Haifa 3109601, Israel.
Yishai OfranThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.
Igal Louria-HayonThe Clinical Research Institute at RAMBAM (CRIR), Rambam Health Care Campus, Haifa 3109601, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lnk is an adaptor protein that attenuates cytokine receptor signaling in hematopoietic and immune cells, but its role in the behavior of CD8

Indexed as

adaptor proteincancer immunotherapyCD8+ T cellschemotaxisCXCR1/2 signalingIL-8 (CXCL8)Lnk (SH2B3)melanomaT-cell traffickingtumor infiltration

Identifiers

PMID42519390
PMCPMC13382576

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.