ArticleJournal of neuroendovascular therapy2026
Successful Retrieval of a Pathologically Proven Calcified Thrombus Using Nimbus: A Case Report.
Article in Journal of neuroendovascular therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Mechanical thrombectomy can be challenging in cases of hard or calcified thrombi that are resistant to conventional aspiration and stent-retriever techniques. The Nimbus stent retriever (Johnson & Johnson, Warsaw, IN, USA) is designed to improve outcomes in cases with hard clots. Case Presentation: An 80-year-old woman presented with an acute ischemic stroke due to left M2 occlusion. Preprocedural imaging revealed a markedly hyperattenuating lesion on CT and a susceptibility effect on T2*-weighted imaging at the occlusion site. During lesion crossing, marked resistance was encountered when advancing the microguidewire and microcatheter. Aspiration and conventional combined techniques failed to achieve recanalization. A Nimbus stent retriever was used as a rescue device. The stent retriever was deployed across the thrombus while aligning its proximal segment with the clot and partially re-sheathed until resistance was encountered, followed by retrieval of the stent retriever and aspiration catheter as a single unit under continuous aspiration. Successful recanalization was achieved (modified Thrombolysis in Cerebral Infarction score 2B). Histopathological examination of the resected specimen revealed a calcified thrombus. Transthoracic echocardiography and chest CT revealed mitral valve calcification. Conclusion: Nimbus may be particularly useful for retrieving calcified or unusually firm thrombi that are resistant to conventional thrombectomy techniques.
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