Evidence map›Paper›PMID 42519362›Full record

ArticleInternational journal of general medicine2026

Nasal Microbiota Associated with the Lung Radiomic Features in Asthma.

Lijuan Hua, Wenxue Bai, Xuezhao Wang, Dongyuan Wang, Mengyao Guo, Lirong Chen, Bingyi Liu, Yi Wang, Shengding Zhang, Xiaoyu Fang and 3 more

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Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Lijuan HuaDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.
Wenxue BaiDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.
Xuezhao WangDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.
Dongyuan WangDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.
Mengyao GuoDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.
Lirong ChenDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.
Bingyi LiuDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.ORCID 0000-0002-3006-5564
Yi WangDepartment of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of Health Ministry, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.
Shengding ZhangDepartment of Pulmonary and Critical Care Medicine, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China.
Xiaoyu FangDepartment of Emergency, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510260, People's Republic of China.
Zhenyu YangDepartment of Rheumatology and Immunology, The Second Clinical Medical College, Jinan University (Shenzhen People's Hospital), Department of Medical Treatment, Shenzhen, Guangdong, 518020, People's Republic of China.
Lu QinDepartment of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Min XieDepartment of Emergency and Critical Care Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.ORCID 0000-0003-4052-1647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aims to characterize the nasal lavage fluid (NLF) microbiota in asthma and explore its relationship with lung radiomic features. Patients and Methods: We collected NLF from 39 participants (12 controls and 27 asthma) for 16S rRNA gene sequencing. Lung radiomics of asthma were analyzed manually and with NeuLungCARE software. The relationships between microbiota and radiomic features were investigated by correlation and regression analyses. Asthma microbiota was further characterized via Jensen-Shannon Divergence (JSD) clustering. Results: After adjusting for sex and age, the asthma group had a significantly elevated NLF bacterial load compared with the control group, while the microbial dysbiosis index (MDI) remained comparable between the two groups. The asthma group exhibited significantly elevated NLF bacterial load compared with the controls ( Conclusion: The NLF microbiota correlated significantly with the lung radiomic, functional, and inflammatory markers. It is highly necessary to conduct further prospective research on the impact of NLF microbiota on the lower airway characteristics of asthma patients.

Indexed as

airway and parenchyma abnormalitiesasthmalung radiomicsnasal microbiota dysbiosis

Identifiers

PMID42519362
PMCPMC13384008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.