How many medicinal slices should be used in an experiment of Chinese medicine extraction process?

Jiale Xie, Bo Chen, Jingmi Liu, Xingchu Gong

Abstract read

In one paragraph

Article in Journal of pharmaceutical analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jiale XiePharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

Bo ChenPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

Jingmi LiuTianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.

Xingchu GongPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The medicinal slice quantity for small-scale extraction experiments significantly impacts the repeatability of experimental results. A novel concept of representative mass of medicinal slices (RMMS) is presented in this work. RMMS is defined as "the minimum mass of medicinal slices required to ensure the repeatability of the extraction results with an acceptable threshold". Using the modified Fangjihuangqi decoction (MFD) as a case study, a method to determine RMMS was shown in this work. The active ingredient yields (AIYs) and dry matter yield (DMY) were used as the process indicators for the extraction of medicinal slices. AIYs and DMY of each medicinal slice in MFD were determined. The herbs with the relatively higher coefficient of variation (CV) value of AIYs and DMYs were identified, which were

Indexed as

Central limit theoremChinese medicinal slicesCoefficient of variationMonte Carlo simulationRepresentative mass of medicinal slices

Identifiers

PMID42519357

DOI10.1016/j.jpha.2026.101562

PMCPMC13382263

What OpenQuestion holds

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.