Evidence map›Paper›PMID 42519269›Full record

ArticleCureus2026

Evaluation of Antihypertensive Medication Adherence and Its Association With Blood Pressure Control Among Hypertensive Patients Attending Outpatient Clinics in Khyber Pakhtunkhwa, Pakistan: A Cross-Sectional Study.

Muhammad Adeel Zafar, Abubakar Ahmad, Abbas Uddin, Imadud Din, Savaid Ali, Iman Masood, Anielka Cristina C Bonilla Arauz, Arish Noor

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Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Muhammad Adeel ZafarAcute Medicine, Royal Glamorgan Hospital, Llantrisant, GBR.
Abubakar AhmadInternal Medicine, District Headquarters Teaching Hospital, Dera Ismail Khan, PAK.
Abbas UddinInternal Medicine, Khyber Medical University, Peshawar, PAK.
Imadud DinInternal Medicine, Khyber Medical University, Peshawar, PAK.
Savaid AliPediatrics, Medical Teaching Institution, Ayub Teaching Hospital, Abbottabad, PAK.
Iman MasoodInternal Medicine, Gomal Medical College, Dera Ismail Khan, PAK.
Anielka Cristina C Bonilla ArauzGeneral Medicine, National Autonomous University of Nicaragua, Leon, NIC.
Arish NoorMedicine, Khyber Medical College, Peshawar, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertension is a major noncommunicable disease in Pakistan, and suboptimal blood pressure (BP) control remains a significant public health challenge, largely influenced by poor adherence to antihypertensive medications.

objectiveThis study aimed to assess the prevalence of antihypertensive medication adherence and its association with BP control among hypertensive patients attending outpatient clinics in Khyber Pakhtunkhwa, Pakistan. METHODOLOGY: This analytical cross-sectional study included 436 hypertensive patients selected through consecutive sampling from tertiary care hospitals. Data were collected using a structured questionnaire and the validated Brief Medication Questionnaire. BP was measured using standardized procedures with a Medico Aneroid Sphygmomanometer AND-85 and the Omron M3 Comfort device (Omron Healthcare, Kyoto, Japan). BP control was defined as <140/90 mmHg. Data were analyzed using Statistical Package for the Social Sciences version 25 (IBM Corp., Armonk, NY). The chi-square test and multivariable binary logistic regression were used to assess associations and adjust for confounders.

resultsOf 436 participants, 196 (44.95%) were adherent and 240 (55.05%) were nonadherent. BP was controlled in 178 (40.83%) patients and uncontrolled in 258 (59.17%). Controlled BP was significantly higher among adherent patients (67.35%) compared with nonadherent patients (19.17%) (P < 0.001). Nonadherence was independently associated with uncontrolled hypertension (adjusted odds ratio = 3.82; 95% confidence interval: 2.45-5.97; P < 0.001). Other significant predictors included age ≥60 years, diabetes mellitus, and longer duration of hypertension.

conclusionMedication nonadherence is a major independent and modifiable determinant of poor BP control among hypertensive patients in Khyber Pakhtunkhwa. Targeted adherence-enhancing interventions are urgently needed in outpatient clinical settings.

Indexed as

blood pressure controlbmqhypertensionmedication adherencepakistan

Identifiers

PMID42519269
PMCPMC13382067

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