Evidence map›Paper›PMID 42519141›Full record

ArticleIDCases2026

Unveiling meropenem-induced thrombocytopenia: Insight from a positive rechallenge case.

Mahdi Aleid, Fatimah Alsaif, Ahmed Alkudaimi, Zahra Hussain Almousa, Bashayer Al Shatti, Zahra Alqaysum, Zahra Noor Alqassab, Jood Ali, Fatimah Aldalouj

Abstract readCase Reports
In one paragraph

Article in IDCases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mahdi AleidDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.
Fatimah AlsaifDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.
Ahmed AlkudaimiDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.
Zahra Hussain AlmousaDepartment of pharmacy, King Fahad Hospital of The university, Khober, Saudi Arabia.
Bashayer Al ShattiDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.
Zahra AlqaysumDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.
Zahra Noor AlqassabDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.
Jood AliDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.
Fatimah AldaloujDepartment of pharmacy, Mouwasat Hospital, Qatif, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meropenem is a broad-spectrum carbapenem antibiotic widely used to treat serious infections.Although generally safe, it can rarely cause drug-induced thrombocytopenia (DITP), a potentially life-threatening condition. We report a case of a 43-year-old male who developed progressive thrombocytopenia after starting meropenem within 3 days, with platelet count recovering upon drug discontinuation. A positive rechallenge with meropenem led to rapid recurrence of thrombocytopenia, giving a probable association. Platelet count improved after permanent cessation of the drug. This case underscores the need for clinicians to be aware of meropenem-induced thrombocytopenia, emphasizing prompt recognition and discontinuation to prevent complications. Regular platelet monitoring during therapy is advised for early detection.

Indexed as

InfectionsMeropenemRechallengeThrombocytopenia

Identifiers

PMID42519141
PMCPMC13382088

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.