Evidence map›Paper›PMID 42518954›Full record

ArticleFrontiers in neurology

Correlations of systemic immune-inflammation index and systemic inflammation response index with the risk for early-onset post-stroke depression in patients with minor stroke: a prospective observational study.

Wei Zhao, Mingzhu Deng, Zhen Wang, Guohua He, Wei Xu, Tieqiao Feng, Jian Peng, Kangping Song, Ling Xiao, Fangyi Li

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In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Wei Zhao *Department of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Mingzhu Deng *Department of Neurology, The Second People's Hospital of Hunan Province (Brain Hospital of Hunan Province), Changsha, Hunan, China.
Zhen WangDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Guohua HeDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Wei XuDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Tieqiao FengDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Jian PengDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Kangping SongDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Ling XiaoDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Fangyi LiDepartment of Neurology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inflammation plays a pivotal role in the pathophysiology of post-stroke depression (PSD). However, the relationship between novel systemic inflammatory indices-the systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI)-and early-onset PSD remains inadequately explored. Methods: Early-onset PSD was diagnosed 2 weeks after acute ischemic stroke (AIS). Depression severity was assessed using the 17-item Hamilton Depression Rating Scale (HAMD-17); patients with scores ≥7 were classified into the early-onset PSD group. Spearman rank correlation analysis was performed to evaluate associations of SII and SIRI with HAMD-17 scores across all participants. Binary logistic regression was used to examine the independent associations of SII and SIRI with early-onset PSD. Receiver operating characteristic (ROC) analysis was employed to assess the SII and SIRI capacity to differentiate early-onset PSD. Results: Of the 1,113 prospectively enrolled patients, 372 (33.42%) were diagnosed with early-onset PSD. HAMD-17 scores showed significant positive correlations with SII ( Conclusion: SII and SIRI may serve as independent risk factors for early-onset PSD. These indices offer potential utility for risk stratification and could inform prevention strategies and prognosis management in this patient population.

Indexed as

depressioninflammationpost-stroke depressionsystemic immune-inflammation indexsystemic inflammation response index

Identifiers

PMID42518954
PMCPMC13381300

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