Evidence map›Paper›PMID 42518917›Full record

ArticleNew microbes and new infections2026

Molecular frequency of

Arezoo Dehghan, Mohammad Hossein Ahmadi, Saber Esmaeili, Mohammad Ali Boroumand, Mahshid Hesami

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in New microbes and new infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Arezoo DehghanDepartment of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran.
Mohammad Hossein AhmadiDepartment of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran.
Saber EsmaeiliWHO Collaborating Centre for Vector-Borne Diseases, Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran.
Mohammad Ali BoroumandDepartment of Pathology and Laboratory Medicine, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Mahshid HesamiCardiogenetic Research Center, Rajaie Cardiovascular Institute, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Infective endocarditis (IE) is a life-threatening condition caused by diverse microbial agents and remains a major diagnostic and therapeutic challenge, particularly in cases of blood culture-negative IE (BCN-IE). Methods: In this cross-sectional study, 405 formalin-fixed paraffin-embedded heart valve tissue samples from 232 patients with pathologically and clinically confirmed IE who underwent valve replacement were collected between March 2021 and March 2025 from two tertiary referral hospitals in Tehran, Iran. Following DNA extraction, Results: Overall, Conclusions: Fastidious and intracellular pathogens are important but overlooked causes of BCN-IE in Iran. Molecular analysis of heart valve tissues represents a valuable diagnostic strategy and supports the need for improved surveillance, prevention, and targeted management of zoonotic and fastidious agents in IE.

Indexed as

BartonellaBlood culture-negative endocarditisBrucellaCoxiella burnetiiInfective endocarditisMolecular diagnosisTropheryma whipplei

Identifiers

PMID42518917
PMCPMC13383017

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.