Evidence map›Paper›PMID 42518879›Full record

ReviewResuscitation plus2026

Deferred cord clamping in twin pregnancies: benefit, risk, or missed opportunity? A narrative review.

Aimann Surak, Graeme Polglase, Georg M Schmölzer

Abstract readReview
In one paragraph

Review in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aimann SurakCentre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, Alberta, Canada.
Graeme PolglaseDepartment of Paediatrics, Monash University, Melbourne, Australia.
Georg M SchmölzerCentre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deferred umbilical cord clamping enhances placental transfusion and is associated with improved outcomes in preterm infants. Following lung aeration and prior to umbilical cord clamping, the increase in pulmonary blood flow contributes to establishing blood volume within the pulmonary vascular bed, which constitutes the mechanism of physiology-based cord clamping. While the benefits of deferred cord clamping have been well described in singleton deliveries, evidence in twin pregnancies remains limited. This is particularly relevant for monochorionic twins, who share a placental circulation and may be at risk of inter-twin transfusion. This narrative review summarizes and critically appraises the available literature on deferred cord clamping in twin pregnancies, with particular emphasis on monochorionic twins. We highlight potential benefits, risks, and current knowledge gaps. Individual Participant Data meta-analyses and adequately powered studies are needed to better evaluate outcomes in multiple gestations, including long-term neurodevelopment.

Indexed as

Deferred cord clampingDelayed cord clampingMonochorionicNeonatal transitionPlacental transfusionResuscitationTwins

Identifiers

PMID42518879
PMCPMC13383940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.