ArticleGastro hep advances2026
Severe Gastrointestinal Graft-versus-Host Disease Following Haploidentical Stem Cell Transplantation Presenting With Passage of a Colonic Cast.
Article in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastrointestinal graft-versus-host disease (GI-GVHD) is a life-threatening complication of allogeneic hematopoietic stem cell transplantation with increased severity in haploidentical settings. We report a fatal case of severe, steroid-refractory GI-GVHD in a 67-year-old male following haploidentical stem cell transplantation for myelodysplastic syndrome with excess blasts-2. The patient developed multiorgan complications including refractory cytopenias, severe infections, pleural effusions, and hepatic dysfunction. A rare and striking manifestation occurred with the passage of a colonic cast, reflecting profound mucosal injury and full-thickness epithelial sloughing. Despite maximal immunosuppressive therapy, including corticosteroids, calcineurin inhibition, ruxolitinib, and extracorporeal photopheresis, the patient deteriorated and ultimately expired. This case highlights an extreme presentation of GI-GVHD with rare colonic cast formation and emphasizes the aggressive nature of steroid-refractory disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.