ArticleESMO real world data and digital oncology2026
Real-world diagnostic pathways and treatment patterns for suspected lung cancer in Japan: a nationwide claims database analysis.
Article in ESMO real world data and digital oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Lung cancer (LC) poses significant diagnostic and therapeutic challenges, particularly regarding accurate and timely diagnosis. This study aimed to assess real-world diagnostic pathways and treatment patterns for suspected LC in Japan, identifying potential inefficiencies and areas for improvement. Materials and methods: A nationwide retrospective analysis was conducted using claims data from ∼28% of Diagnosis Procedure Combination hospitals in Japan, encompassing patients with suspected LC between 2008 and 2023. Diagnostic methods, biopsy utilization, treatment modalities, and intervals from suspicion to diagnosis and treatment initiation were analyzed. Results: Of the 757 397 patients studied (mean age 66.7 years; 56.0% male), 23.0% ( Conclusions: Significant gaps were identified in LC diagnosis in Japan, including overreliance on imaging without sufficient biopsy validation and unnecessary invasive procedures. Improving biopsy utilization and adopting advanced bronchoscopic methods, alongside reconsidering current screening practices, could enhance diagnostic accuracy, patient outcomes, and resource efficiency.
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