Evidence map›Paper›PMID 42518671›Full record

ArticleUrology case reports2026

Prostate cancer-associated Trousseau's syndrome presenting as stroke in a 42-year-old man.

Yosuke Tsukii, Tomoki Okada, Gensuke Okazaki, Yuya Ota, Satoshi Kurokawa, Takahiro Yasui

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yosuke TsukiiDepartment of Urology, Anjo Kosei Hospital, Anjo, Japan.
Tomoki OkadaDepartment of Urology, Anjo Kosei Hospital, Anjo, Japan.
Gensuke OkazakiDepartment of Urology, Anjo Kosei Hospital, Anjo, Japan.
Yuya OtaDepartment of Urology, Anjo Kosei Hospital, Anjo, Japan.
Satoshi KurokawaDepartment of Urology, Anjo Kosei Hospital, Anjo, Japan.
Takahiro YasuiDepartment of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 42-year-old man presenting with acute left hemiparesis and multiple cerebral infarctions accompanied by markedly elevated D-dimer levels, suggesting cancer-associated thrombosis without an identifiable primary malignancy. Six months later, he was diagnosed with advanced prostate adenocarcinoma with multiple bone metastases and a markedly elevated prostate-specific antigen level. Treatment with apalutamide and degarelix was initiated. Despite early recurrent thromboembolic events, PSA and D-dimer levels gradually decreased. At 10 months, both markers were significantly reduced and no further thrombosis occurred. This case highlights prostate cancer as a potential cause of cryptogenic stroke and importance of cancer-directed therapy for Trousseau's syndrome.

Indexed as

Bone metastasesD-dimerProstate cancerTrousseau's syndrome

Identifiers

PMID42518671
PMCPMC13383011

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.