Evidence map›Paper›PMID 42518668›Full record

ArticleUrology case reports2026

Primary signet-ring carcinoma of the urinary bladder: A case report and mini review of literature.

Binyam Mohammedbirhan Berhe, Birhanu Kassie Reta, Haftom Guesh Girmay, Daniel Kassie Molla, Tariku Mulatu Bore, Melaku Abay Muluneh, Seydu Worku

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Binyam Mohammedbirhan BerheMekelle University, College of Health Sciences, Department of Pathology, Mekelle, Ethiopia.
Birhanu Kassie RetaAxum University, College of Health Sciences, Department of Pathology, Aksum, Ethiopia.
Haftom Guesh GirmayAxum University, College of Health Sciences, School of Medicine, Aksum, Ethiopia.
Daniel Kassie MollaJigjijga University, College of Health Sciences, Department of Pathology, Jigjijga, Ethiopia.
Tariku Mulatu BoreALERT Comprehensive Specialized Hospital, Department of Pathology, Addis Ababa, Ethiopia.
Melaku Abay MulunehArsi University College of Health Sciences, Department of Pathology, Asela, Ethiopia.
Seydu WorkuBahir Dar University College of Health Sciences, School of Medicine, Bahir Dar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary signet ring cell carcinoma (SRCC) of the urinary bladder is an exceptionally rare and aggressive malignancy. We report a case of a 60-year-old man presenting with painless gross hematuria, urinary frequency, and dysuria. Imaging and cystoscopy revealed a bladder lesion, while histopathology demonstrated diffuse signet ring cell infiltration with detrusor muscle invasion, confirming muscle-invasive disease. Extensive investigations, including upper and lower gastrointestinal endoscopy, chest radiography, and prostate biopsy, excluded secondary malignancies. Despite the lack of immunohistochemistry, diagnosis was established through clinicopathologic correlation. This case highlights the importance of thorough evaluation for accurate diagnosis and appropriate management.

Indexed as

HematuriaMuscle-invasive bladder cancerSignet ring cell carcinomaUrinary bladder

Identifiers

PMID42518668
PMCPMC13383854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.