ArticlePaediatrics & child health2026
Atropine for the treatment of paediatric sialorrhea: a retrospective case series.
Article in Paediatrics & child health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Objectives: This retrospective case series examined the efficacy of sublingual atropine drops for paediatric patients with sialorrhea followed at the multidisciplinary sialorrhea clinic at Children's Hospital, London Health Sciences Centre. Methods: A retrospective review of patients seen for management of sialorrhea at the multidisciplinary sialorrhea clinic between January 1, 2015 and September 30, 2023 was completed. Patient demographics, comorbidities, interventions, frequency and severity of sialorrhea, and adverse effects were recorded. Drooling frequency and severity scale (DFSS) scores were collected to examine the effectiveness of atropine sublingual drops. A descriptive analysis and Wilcox signed-rank tests were conducted to compare pre- and post-treatment DFSS scores. Results: Twenty-one patients were included in the final analysis. The median DFSS score pretreatment was 4 for frequency and 4 for severity. Post-treatment, the median DFSS score decreased to 3 for both frequency (P = 0.006) and severity (P = 0.003), representing a statistically and clinically significant change. Conclusion: Atropine sublingual drops demonstrated efficacy for decreasing both drooling frequency and severity in a paediatric patient population.
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