ArticleFrontiers in endocrinology2026
Comparison of the effectiveness of autofluorescence devices in the detection of parathyroid glands during thyroid operations: a propensity score matched analysis (PSM).
Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: In recent years, an abundance of evidence has supported the use of specialized autofluorescence devices to assist in detecting parathyroid glands (PGs) during thyroid surgery. This study compares the "naked eye" (NE) method with an alternative device (IMAGE1 S™ Rubina Methods: From 01/01/2024 to 31/08/2025, data from all patients undergoing thyroid-related surgery were collected from a prospectively maintained database. Adult patients who had total thyroidectomy with or without bilateral central neck dissection were included. Patients with concurrent hyperparathyroidism or renal insufficiency were excluded. In the intervention groups, the IMAGE1 S™ Rubina Results: 292 patients were included in the study. Propensity Score Matching yielded 37 patients per group, with no differences in demographic or clinical features. Ordinal logistic regression for the number of parathyroid glands identified showed higher odds of better gland identification with Rubina Conclusion: Detection rates of parathyroid glands improved with the use of both autofluorescence devices compared to the naked eye, while there was no significant decrease in postoperative hypoparathyroidism rates.
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