Evidence map›Paper›PMID 42518493›Full record

ArticleSurgery open science2026

Assessment of infiltrative margins in subcutaneous soft-tissue sarcomas using ultrasonography and gadolinium-enhanced fat-suppressed T1-weighted imaging.

Jun Iwatsu, Munenori Watanuki, Shinichirou Yoshida, Hirotaka Kurata, Shin Hitachi, Sota Oguro, Mika Watanabe, Toshimi Aizawa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgery open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jun IwatsuTohoku University Graduate School of Medicine, Department of Orthopedic Surgery, 1-1 Seiryomachi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.
Munenori WatanukiJR Sendai Hospital, Department of Orthopedic Surgery, 1-1-5 Itsutsubashi, Aoba-ku, Sendai, Miyagi, 980-8508, Japan.
Shinichirou YoshidaTohoku University Graduate School of Medicine, Department of Orthopedic Surgery, 1-1 Seiryomachi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.
Hirotaka KurataTohoku University Graduate School of Medicine, Department of Orthopedic Surgery, 1-1 Seiryomachi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.
Shin HitachiTakeda General Hospital, Department of Diagnostic Radiology, 3-27 Yamagamachi, Aizuwakamatsu, Fukushima, 965-8585, Japan.
Sota OguroTohoku University Hospital, Department of Diagnostic Radiology, 1-1 Seiryomachi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.
Mika WatanabeTohoku Kosai Hospital, Department of Pathology, 2-3-11 Kokubuncho, Aoba-ku, Sendai, Miyagi, 980-0803, Japan.
Toshimi AizawaTohoku University Graduate School of Medicine, Department of Orthopedic Surgery, 1-1 Seiryomachi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) aids in detecting infiltrative growth; however, preoperative determination of the extent of soft-tissue sarcoma (STS) infiltration remains challenging. Ultrasonography could also detect infiltration effectively. We investigated the usefulness of MRI and ultrasonography as preoperative assessments for infiltrative STS. We retrospectively evaluated the data of 24 patients with subcutaneous infiltrative STS. Infiltrative length was measured using gadolinium-enhanced fat-suppressed T1-weighted imaging (GdFsT1) (M-IL) and ultrasonography (U-IL). The reactive layer was set at a greater distance of M-IL or U-IL. The surgical margin was set at greater distance of 2 cm from the tumor edge or 1.5 cm beyond the reactive layer. Histological infiltrative length (H-IL) and histological surgical margin length (H-margin) were measured using specimens. Relationships among M-IL, U-IL, and H-IL were analyzed using Spearman's rank correlation coefficients. Clinical outcomes, such as overall survival (OS) and local recurrence (LR), were evaluated using the Kaplan-Meier method. In 19 of 64 directions, H-IL was wider than M-IL. Among the 19 directions, U-IL was wider than H-IL in 11 directions, whereas H-IL was wider than U-IL in 8 directions. Mean H-margin was 29 mm, and the margin was negative in all directions. Spearman's correlation revealed weak associations between H-IL and M-IL (ρ = 0.08,

Indexed as

InfiltrationMagnetic resonance imagingPreoperative assessmentSoft tissue sarcomaUltrasonography

Identifiers

PMID42518493
PMCPMC13383016

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