Evidence map›Paper›PMID 42518490›Full record

ArticleBBA advances2026

Single-stranded nucleic acid binding enhances the in vitro catalytic activity of Chikungunya virus nsP2 protease.

Mohammadamin Mastalipour, Danilo Silva Olivier, Mônika Apareçida Coronado, Andrew J Dingley, Ruth Anasthasia Siahaan, Alissa Drees, Christian Ahlers, Markus Fischer, Dieter Willbold, Raphael Josef Eberle

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In one paragraph

Article in BBA advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammadamin MastalipourInstitut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Danilo Silva OlivierIntegrated Sciences Center, Campus Cimba, Federal University of Tocantins, Araguaína, 77824-838, TO, Brazil.
Mônika Apareçida CoronadoInstitut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Andrew J DingleyInstitut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Ruth Anasthasia SiahaanFaculty of Chemistry and Biotechnology, FH Aachen, Campus Jülich, Germany.
Alissa DreesHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Hamburg, Germany.
Christian AhlersHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Hamburg, Germany.
Markus FischerHamburg School of Food Science, Institute of Food Chemistry, University of Hamburg, Hamburg, Germany.
Dieter WillboldInstitut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Raphael Josef EberleInstitut für Biochemische Pflanzenphysiologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya virus (CHIKV) is an emerging arbovirus whose replication relies on the multifunctional nonstructural protein 2 (nsP2), particularly its viral protease (nsP2

Indexed as

AptamersChikungunya virusnsP2 protease (nsP2pro)Protein–nucleic acid interactionSingle-stranded nucleic acidViral replication

Identifiers

PMID42518490
PMCPMC13383954

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.