Evidence map›Paper›PMID 42518468›Full record

ArticleACS omega2026

Novel Inhibitors Targeting Urease Promote Fungicidal and Antivirulence Effects in

Thayná Lopes Barreto, Nathália Evelyn Morais Costa, Nathalia Monteiro Lins Freire, Larissa Costa de Almeida, Rodrigo Dos Anjos Miguel, Leticia Veras Costa-Lotufo, Gislaine da Silva-Rodrigues, Cleiton Moreira da Silva, Thiago Mendonça de Aquino, Eduardo Eliezer Alberto and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thayná Lopes BarretoDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 1374 Prof. Lineu Prestes Avenue, São Paulo, São Paulo 05508-000, Brazil.
Nathália Evelyn Morais CostaDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, 6627 Pres. Antônio Carlos Avenue, Belo Horizonte, Minas Gerais 31270-901, Brazil.
Nathalia Monteiro Lins FreireResearch Group on Therapeutic Strategies - GPET, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, Maceió, Alagoas 57072-900, Brazil.
Larissa Costa de AlmeidaDepartment of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, 1524 Prof. Lineu Prestes Avenue, São Paulo, São Paulo 05508-000, Brazil.
Rodrigo Dos Anjos MiguelDepartment of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, 1524 Prof. Lineu Prestes Avenue, São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0002-4965-1168
Leticia Veras Costa-LotufoDepartment of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, 1524 Prof. Lineu Prestes Avenue, São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0003-1861-5153
Gislaine da Silva-RodriguesDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 1374 Prof. Lineu Prestes Avenue, São Paulo, São Paulo 05508-000, Brazil.
Cleiton Moreira da SilvaDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, 6627 Pres. Antônio Carlos Avenue, Belo Horizonte, Minas Gerais 31270-901, Brazil.ORCID https://orcid.org/0000-0001-9913-8971
Thiago Mendonça de AquinoResearch Group on Therapeutic Strategies - GPET, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Lourival Melo Mota Avenue, Maceió, Alagoas 57072-900, Brazil.
Eduardo Eliezer AlbertoDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, 6627 Pres. Antônio Carlos Avenue, Belo Horizonte, Minas Gerais 31270-901, Brazil.
Ângelo de FátimaDepartment of Chemistry, Institute of Exact Sciences, Federal University of Minas Gerais, 6627 Pres. Antônio Carlos Avenue, Belo Horizonte, Minas Gerais 31270-901, Brazil.ORCID https://orcid.org/0000-0003-3010-695X
Kelly IshidaDepartment of Microbiology, Institute of Biomedical Sciences, University of São Paulo, 1374 Prof. Lineu Prestes Avenue, São Paulo, São Paulo 05508-000, Brazil.ORCID https://orcid.org/0000-0002-4602-0926

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcosis is a life-threatening fungal disease caused by the

Identifiers

PMID42518468
PMCPMC13382658

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.