ReviewACS omega2026
Focused Review on pH- and Temperature-Responsive Pectin-Based Hydrogels for Drug Delivery and Controlled Release Applications.
Review in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stimuli-responsive hydrogels demonstrate an intelligent ability to respond to environmental triggers, such as pH, temperature, etc. Such an ability has been applied to the control release drug delivery system to specific sites with controllable kinetics. Natural macromolecules, especially pectin, have a high potential to develop into stimuli-responsive hydrogels for biomedical applications due to their versatile gelling properties, high biocompatibility, biodegradability, and nontoxicity. Furthermore, the chemical structure of pectin also offers modifications through various chemical reactions to enhance the ability of responding to external triggers under physiological conditions. While pectin has been widely studied in drug delivery, its potential as a smart hydrogel for site-specific, stimuli-responsive drug release remains underexplored. This review highlights recent advancements in pectin modifications to improve its responsiveness to pH and temperature variations, which are crucial for biomedical applications. Additionally, the underlying mechanisms governing these behaviors in pectin-based hydrogels are discussed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.