ArticleACS omega2026
Lysozyme-Loaded Rough Calcium Alginate Hydrogel Film for Antibacterial Wound Dressing.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lysozyme-loaded antibacterial wound dressings hold great promise for wound healing. Herein, we propose a simple yet powerful method of loading antibacterial lysozyme into calcium alginate (CaAlg) hydrogel films for wound healing. This method presents a controlled strategy to modulate the surface roughness of CaAlg hydrogel films by tailoring their thickness, thereby enhancing the lysozyme loading efficiency on the film surface. We fabricated CaAlg hydrogel films with gradient thicknesses by adjusting the copper wire diameters. Morphological characterization confirmed that the surface of the thin CaAlg film is rougher than that of the thick ones. This enhanced surface roughness conferred a larger specific surface area, which effectively promoted the adsorption of lysozyme and, thus, improved the enzyme loading capacity. The release of lysozyme after adsorption and the interactions between lysozyme and alginate were also investigated, and the results showed that approximately 7.5 mg/g lysozyme can be released from the film. Therefore, the lysozyme-loaded CaAlg film (CaAlg-lysozyme) exhibited excellent antibacterial properties. In vivo results showed that the CaAlg-lysozyme film could promote wound healing. The percentages of wound healing of the untreated group, gauze, and CaAlg-lysozyme film were 65.36, 77.78, and 91.43% on day 10, respectively, indicating the great potential of CaAlg-lysozyme film as a practical wound dressing.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.