ArticleACS omega2026
Flow-Through Aptamer-SERS Microfluidic Platform for Aflatoxin B1 Detection in Food Crops.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Microfluidics-Integrated Spectroscopic Technologies for Food Safety and Quality Assessment: From Complex-Matrix Processing to On-Site Decision-Making.Foods (Basel, Switzerland) · 2026Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycotoxins are secondary metabolites produced by fungal species. Due to its high toxicity, Aflatoxin B1 (AFB1) is one of the most hazardous mycotoxins found in various food crops. The ability to detect such a toxin is therefore important for the safe consumption and handling of large quantities of crops. For this, surface-enhanced spectroscopy provides the sensitivity to detect low concentrations of analytes but is limited in terms of specificity toward a given analyte. This work explores how to enhance the selectivity of a SERS active platform by conjugating it with aptamers designed to specifically recognize AFB1 target molecules. A robust flow-through lab-on-a-chip platform with an integrated SERS gold nanohole array functionalized with an aptamer (apta-SERS) was developed and tested on real samples, demonstrating rapid, high-affinity toxin detection. The sensitivity of the nanoholes was evaluated in the range of 10-700 ppb, and in the presence of a complex matrix such as food crop extracts, a limit of detection of 10 ppb was reached. Such a platform enables
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Registered trials
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