Evidence map›Paper›PMID 42518391›Full record

ArticleACS omega2026

Cyclic Mechanical Deformation of Denture PMMA Regulates Fungal Biofilm Virulence.

Carolina Montoya, Ryan Yu-Sheng Chang, Dmitriy A Dikin, Mike Sousanieh, Zhenting Xiang, Yuan Liu, Sumant Puri, Santiago Orrego

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carolina MontoyaDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, Pennsylvania 19140, United States.
Ryan Yu-Sheng ChangDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, Pennsylvania 19140, United States.
Dmitriy A DikinPhysics Department, College of Science and Technology, Temple University, Philadelphia, Pennsylvania 19122, United States.
Mike SousaniehGCDLab, Prospect Heights, Illinois 60070, United States.
Zhenting XiangDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, Pennsylvania 19140, United States.
Yuan LiuDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, Pennsylvania 19140, United States.
Sumant PuriDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, Pennsylvania 19140, United States.ORCID https://orcid.org/0000-0002-5509-007X
Santiago OrregoDepartment of Oral Health Sciences, Kornberg School of Dentistry, Temple University, Philadelphia, Pennsylvania 19140, United States.ORCID https://orcid.org/0000-0003-3683-6750

Funding

Pathogenesis of oral microbes triggered by the cyclic deformation of biomaterialsR56DE034026 · NIDCR · TEMPLE UNIV OF THE COMMONWEALTH · PI ORREGO, SANTIAGO · 2024 to 2024
$656k
NIDCR NIH HHS R56 DE034026
6 · The paper itself

Abstract

Cyclic mechanical deformation is a well-characterized phenomenon in polymeric biomaterials under physiological mastication loading, yet its role in regulating biological responses at material interfaces remains poorly understood. Here, we investigate whether cyclic mechanical loading of denture-base poly-(methyl methacrylate) (PMMA) functions as a biomaterial-derived cue that regulates fungal biofilm behavior. This study establishes that mechanically induced

Identifiers

PMID42518391
PMCPMC13382762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.