Evidence map›Paper›PMID 42518108›Full record

ArticleMolecular biology reports2026

Genome-wide identification and characterization of the glutaredoxin (GRX) family genes in wild soybean and their expression dynamics under salt and alkali conditions.

Resham Khan, Zhang Chengbo, Aiza Zahid, Naila Ali, Arshia Tariq, Athar Mutahari, Binish Khaliq, Anis Ali Shah, Asfa Batool, Chen Chao and 2 more

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Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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12 authors.

Resham KhanInstitute of Molecular Biology and Biotechnology IMBB, The University of Lahore, Lahore, Pakistan.
Zhang ChengboDepartment of Chemistry and Molecular Biology, School of Life Science and Technology, Harbin Normal University, Harbin, 150025, P.R. China.
Aiza ZahidInstitute of Molecular Biology and Biotechnology IMBB, The University of Lahore, Lahore, Pakistan.
Naila AliInstitute of Molecular Biology and Biotechnology IMBB, The University of Lahore, Lahore, Pakistan.
Arshia TariqInstitute of Molecular Biology and Biotechnology IMBB, The University of Lahore, Lahore, Pakistan.
Athar MutahariDepartment of Biochemistry and Biotechnology, University of Gujrat, Gujrat, Pakistan.
Binish KhaliqDepartment of Botany, University of Okara, Okara, Pakistan.
Anis Ali ShahDepartment of Botany, Division of Science and Technology, University of Education, Lahore, Pakistan.
Asfa BatoolState Key Laboratory of Herbage Improvement and Grassland Agro-Ecosystems, College of Ecology, Lanzhou University, Lanzhou, 730000, P.R. China.
Chen ChaoDepartment of Chemistry and Molecular Biology, School of Life Science and Technology, Harbin Normal University, Harbin, 150025, P.R. China. chchao@hrbnu.edu.cn.
Zaib Un NisaInstitute of Molecular Biology and Biotechnology IMBB, The University of Lahore, Lahore, Pakistan. zaib.nisa@imbb.uol.edu.pk.
Mansour K GatashehDepartment of Biochemistry, College of Science, King Saud University, P.O.Box 2455, Riyadh, 11451, Saudi Arabia.

Funding

Graduate innovation research project of Harbin Normal University HSDSSCX2022-140Heilongjiang Natural Science Foundation YQ2023C034Ongoing Research Funding program ORF-2026-393
6 · The paper itself

Abstract

backgroundGlutaredoxins (GRXs) are vital oxidoreductases governing plant redox homeostasis, growth, development and stress adaptation. Although GRXs carry essential biological functions, the GRX gene family in wild soybean (Glycine soja Sieb and Zucc.) lacks systematic characterization. This genome-wide study aimed to identify and profile wild soybean GRX genes and explore their functions in salt stress tolerance. METHODS AND

resultsHidden Markov Model screening retrieved 196 candidate GRX proteins; 54 non-redundant GsGRX genes were validated via domain identification and redundancy filtering (sample set: whole wild soybean genome). The encoded proteins varied widely in sequence length, molecular weight, isoelectric point, stability and hydropathicity. Most GsGRXs localized to chloroplasts, with partial distribution in mitochondria, cytoplasm and nucleus. Segmental and tandem duplications drove GsGRX family expansion, and collinearity confirmed conserved evolutionary relationships with Arabidopsis thaliana and Oryza sativa. Promoters contained abundant cis-elements linked to light, hormone and abiotic stress signaling. qRT-PCR showed time-dependent (0, 3, 6 h) transcriptional fluctuations of GsGRX genes under saline-alkali stress.

conclusionsTranscriptional dynamics under stress verify the participation of GsGRX genes in plant stress regulatory networks. This work establishes the first full-scale characterization of the G. soja GRX family, uncovering novel evidence for their core roles in cellular redox control and salt stress resistance in wild soybean.

Indexed as

GlutaredoxinsGlycine maxGene Expression ProfilingGene Expression Regulation, PlantGenome, PlantGenome-Wide Association StudyMultigene FamilyPhylogenyPlant ProteinsPromoter Regions, GeneticSalt StressSalt ToleranceStress, PhysiologicalGlutaredoxinsPlant ProteinsCis-elementsExpression analysisGlutaredoxinGlycine sojaSaline stressSoybean

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PMID42518108

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