Evidence map›Paper›PMID 42518082›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026

Genomic analysis of Streptococcus pyogenes emm1-type isolates reveals M1

Gisele Aparecida Bernardi, Luiza Souza Rodrigues, José Ferreira da Cunha Neto, Geiziane Aparecida Gonçalves, Lavinia Nery Villa Stangler Arend, Sabrina da Conceição Barbosa, Marcelo Pillonetto, Tadayoshi Ikebe, Yukihiro Akeda, Norihiko Takemoto and 1 more

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Gisele Aparecida BernardiLaboratory of Emerging Infectious Diseases - Pontifícia, Universidade Católica Do Paraná, Rua Imaculada Conceição, 1155, Curitiba, Paraná, 80215-901, Brazil.
Luiza Souza RodriguesLaboratório Central Do Estado Do Paraná (LACEN/PR), São José Dos Pinhais, Paraná, Brazil.
José Ferreira da Cunha NetoLaboratório Central Do Estado Do Paraná (LACEN/PR), São José Dos Pinhais, Paraná, Brazil.
Geiziane Aparecida GonçalvesLaboratório Central Do Estado Do Paraná (LACEN/PR), São José Dos Pinhais, Paraná, Brazil.
Lavinia Nery Villa Stangler ArendLaboratório Central Do Estado Do Paraná (LACEN/PR), São José Dos Pinhais, Paraná, Brazil.
Sabrina da Conceição BarbosaLaboratório Central Do Estado Do Paraná (LACEN/PR), São José Dos Pinhais, Paraná, Brazil.
Marcelo PillonettoLaboratório Central Do Estado Do Paraná (LACEN/PR), São José Dos Pinhais, Paraná, Brazil.
Tadayoshi IkebeDepartment of Bacteriology 1, National Institute of Infectious Diseases, Japan Institute for Health Security (JIHS), Tokyo, Japan.
Yukihiro AkedaDepartment of Bacteriology 1, National Institute of Infectious Diseases, Japan Institute for Health Security (JIHS), Tokyo, Japan.
Norihiko Takemoto *Department of Infectious Diseases, National Institute of Global Health and Medicine, Japan Institute for Health Security (JIHS), 1-21-1, Toyama, Shinjuku-Ku, Tokyo, 162-8655, Japan. takemoto.n@jihs.go.jp.
Felipe Francisco Tuon *Laboratory of Emerging Infectious Diseases - Pontifícia, Universidade Católica Do Paraná, Rua Imaculada Conceição, 1155, Curitiba, Paraná, 80215-901, Brazil. felipe.tuon@pucpr.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStreptococcus pyogenes (GAS) causes diseases ranging from mild pharyngitis to severe invasive infections. The emm1 type is the most prevalent worldwide, and a highly transmissible variant, M1

objectiveTo characterize the genomic diversity of invasive GAS isolates collected from severe cases and epidemiologically important outbreaks in Brazil.

methodsWhole-genome sequencing was performed on 229 invasive GAS isolates collected in Brazil between January 2023 and November 2024. Genomes were analyzed for emm typing, lineage assignment, and virulence gene profiling. Comparative genomic analyses, including global M1

resultsThirty-four distinct emm types were identified, with emm1 accounting for 52.4%. Of these, 14% were confirmed as M1

conclusionThe detection of M1

Indexed as

Emm-typeGroup A beta-haemolytic StreptococcusStreptococcus pyogenesWhole genome sequencing

Identifiers

PMID42518082

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.