ArticleMolecular neurobiology2026
The Investigation of MicroRNA Expression Levels in Postmortem Nucleus Accumbens of the Individuals with 6-MAM-Confirmed Heroin-Associated Polysubstance İntoxication: A Case Control Study.
Article in Molecular neurobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
MicroRNAs, small noncoding RNA molecules, are pivotal regulators of gene expression and have been increasingly implicated in the molecular mechanisms underlying addiction. In this study, we investigated microRNA expression profiles in postmortem nucleus accumbens tissue, a key brain region for reward and addiction, from individuals with 6-monoacetylmorphine confirmed heroin-associated polysubstance intoxication (6-MAM-HAPI) (n = 20) compared with non-user individuals (n = 20). Total RNA was isolated from the tissues with "RNAzol®RT," and cDNA was obtained and measured by qRT-PCR. MicroRNA expression levels were calculated by the 2
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