High-sensitivity immunochromatographic assay based on time-resolved fluorescence microspheres for the simultaneous detection of mescaline and LSD in hair.

Moying Yang, Wu Wen, Hongxian Yang, Bin Di, Jie Chen, Mengxiang Su

Abstract read

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Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Moying YangDepartment of Pharmacy, China Pharmaceutical University, No. 24 Tongjiaxiang Road, Nanjing, 210009, PR China.

Wu WenKey Laboratory of Drug Monitoring and Control, Drug Intelligence and Forensic Center, Ministry of Public Security, Beijing, 100193, PR China.

Hongxian YangKey Laboratory of Drug Monitoring and Control, Drug Intelligence and Forensic Center, Ministry of Public Security, Beijing, 100193, PR China.

Bin DiDepartment of Pharmacy, China Pharmaceutical University, No. 24 Tongjiaxiang Road, Nanjing, 210009, PR China.

Jie ChenKey Laboratory of Drug Monitoring and Control, Drug Intelligence and Forensic Center, Ministry of Public Security, Beijing, 100193, PR China. 13501060176@139.com.

Mengxiang SuDepartment of Pharmacy, China Pharmaceutical University, No. 24 Tongjiaxiang Road, Nanjing, 210009, PR China. sumengxiang@cpu.edu.cn.ORCID http://orcid.org/0000-0001-7866-2942

Funding

Key Laboratory of Drug Monitoring and Control, Ministry of Public Security 2023-KLDMC-06

6 · The paper itself

Abstract

Mescaline and lysergic acid diethylamide (LSD) are strong psychedelics that significantly compromise social safety and public health. Satisfying the rapid detection requirements for public security drug enforcement is challenging because of the high costs and long durations associated with gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS). To address these challenges, this study established an immunochromatographic method for the simultaneous detection of mescaline and LSD in hair based on time-resolved fluorescent microspheres. By optimizing key parameters such as the type and pH of the activation buffer, the pH of the labeling buffer, the concentrations of the detection lines (T

Indexed as

HairImmunochromatographicLSDMescalineTime-resolved fluorescence

Identifiers

PMID42517918

DOI10.1093/jat/bkaa089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.