Evidence map›Paper›PMID 42517467›Full record

SynthesisThe International journal of health planning and management2026

Economic Impact of Dengue Virus in Mexico Over One Decade: A Systematic Literature Review (2010-2020).

Gilberto Sánchez-González, Luz Del C Hernández-Hernández, Elaine Gallagher

Abstract readSystematic Review
In one paragraph

Synthesis in The International journal of health planning and management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gilberto Sánchez-GonzálezCentro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México.ORCID https://orcid.org/0000-0002-4322-0084
Luz Del C Hernández-HernándezIndependent Consultant, Cuernavaca, Morelos, México.
Elaine GallagherTakeda Pharmaceuticals International AG, Zurich, Switzerland.

Funding

Takeda Pharmaceuticals International
6 · The paper itself

Abstract

backgroundDengue is a major mosquito-borne viral disease worldwide, imposing significant healthcare burden on governments in countries where it is endemic, such as Mexico. This systematic review focused on studies reporting the cost of dengue in Mexico during 2010-2020. To the best of our knowledge, this is the first review discussing this topic in Mexico. We analysed all published direct costs associated with care, prevention, and surveillance, as well as indirect costs.

methodsA comprehensive online search was conducted using Embase, MEDLINE, Evidence-Based Medicine Reviews, SciELO, and LILACS. Articles reporting cost data published during 2010-2020 in English and Spanish were included. Reports from the National Ministry of Health and grey literature during the same period were also reviewed. Following the PICOS (Population, Intervention, Comparison, Outcome and Study design) framework, articles reporting direct and indirect costs were included. The National Health Service Wales tool was used to assess the quality of the studies included.

resultsSeven articles fulfiled the inclusion criteria. All articles reported the nationwide cost of dengue, and three focused on specific Mexican states. The dengue-related economic burden was substantial, peaking in 2013, with annual costs of $176.82 million (adjusted present value, $281.60 million). All the searches were verified in January 2023.

conclusionsThe economic burden of dengue in Mexico is high and is further impacted by outbreaks, resulting in significant costs to the healthcare system and productivity losses. The heterogeneity of the methodological approaches in the cost studies reviewed makes it a challenge to compare them.

Indexed as

Cost of IllnessDengueHealth Care CostsDengue VirusHumansMexicoburdendengueeconomicMexicoreview

Identifiers

PMID42517467
PMCPMC13551542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.