ArticleFrontiers in public health2026
Association between environmental mold exposure and mild cognitive impairment in older adults: a case-control study.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Cognitive disorders have been associated with exposure to environmental molds in case series and animal experimental models. Older adults spend a substantial proportion of their time indoors, where they may be exposed to household mold contamination. Objective: To determine the association between indoor environmental mold exposure and amnestic mild cognitive impairment (aMCI) among older adults in Bucaramanga during 2024-2025. Methods: A case-control study (1:1 ratio) was conducted, including 60 cases and 60 controls, matched by sex, age, and neighborhood of residence. Cases were selected from the INTERCOG study and controls from the general population. Data collection included participant and housing characterization, the Dampness and Mold Assessment Tool for General Buildings (DMAT), and an assessment of Sick Building Syndrome (SBS) related symptoms. Air culture samples were collected from bedrooms, living rooms, and kitchens. Indoor CO Results: Most participants were female, with a median age of 69 years. aMCI was significantly associated with increased odds of SBS-related nasal irritation (OR = 5.84; 95%CI: 1.20-28.37). The presence of Conclusion: Nasal irritation experienced indoor and relieved upon leaving the home was significantly associated with aMCI. Positive but non-significant associations were observed for the presence of
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