ArticleHealth science reports2026
Substance P and NK-1R in Dengue: A First Serological Investigation.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Substance P and NK-1R in Dengue: A First Serological Investigation.Health science reports · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Dengue fever lacks reliable biomarkers to explain its complex pathophysiology. Substance P (SP) and its receptor, the Neurokinin-1 receptor (NK1R), known regulators of inflammation and vascular permeability in viral infections, may play a role in dengue but remain unexplored. Aim/Objective: To investigate the levels of SP and NK1R in serum samples of diagnosed dengue patients. Methods: Participants were selected from a pool of diagnosed dengue fever patients using a convenience sampling technique ( Results: The mean NK1R levels in the control and case groups were 2.681 ± 3.147 and 0.57 ± 0.131, respectively. NK1R levels were significantly lower in dengue patients compared with controls ( Conclusion: NK1R may be associated with dengue pathogenesis through its potential involvement in vascular permeability, immune activation, and cytokine responses. These findings suggest a possible connection between NK1R and the pathophysiological mechanisms underlying dengue infection.
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