Evidence map›Paper›PMID 42516804›Full record

ReviewOncology letters2026

Systems biology of Wnt signaling in glioma chemotherapy resistance: Integrating multi-omics mechanisms and emerging therapeutic vulnerabilities (Review).

Qianru Zeng, Zhuojun Chen, Rendong Zhang, Hongchao Pan

Abstract readReview
In one paragraph

Review in Oncology letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qianru ZengCentral Laboratory, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Zhuojun ChenCentral Laboratory, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Rendong ZhangThe Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.
Hongchao PanCentral Laboratory, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong 515041, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temozolomide (TMZ) resistance remains a key clinical challenge in treating glioma and a primary cause of tumor recurrence and therapeutic failure. Beyond well-established O

Indexed as

chemoresistancecisplatingliomaglioma stem cellsmetabolic reprogrammingmulti-omicsnanomedicinesystems biologytemozolomideWnt signaling pathway

Identifiers

PMID42516804
PMCPMC13403480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.