Evidence map›Paper›PMID 42516795›Full record

ArticleNorthern clinics of Istanbul2026

Researching impaired heart rate recovery index in patients who have had COVID-19.

Muhammet Fatih Genisoglu, Zuhal Aydan Saglam, Ece Nur Gezgin, Ahmet Oz

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Article in Northern clinics of Istanbul, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Muhammet Fatih GenisogluDepartment of Family Medicine, Istanbul Training and Research Hospital, Istanbul, Turkiye.
Zuhal Aydan SaglamDepartment of Family Medicine, Istanbul Training and Research Hospital, Istanbul, Turkiye.
Ece Nur GezginDepartment of Family Medicine, Istanbul Training and Research Hospital, Istanbul, Turkiye.
Ahmet OzDepartment of Cardiology, Istanbul Training and Research Hospital, Istanbul, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHeart rate recovery index (HRRI) occurs as a result of vagal reactivation and sympathetic retraction and is an independent risk factor used to assess autonomic nervous system (ANS) function and to determine prognosis in cardiovascular disease and all-cause mortality. It has been shown in various studies that cardiac autonomic dysfunction due to COVID-19 can occur. The aim of our study is to evaluate the effect of COVID-19 on ANS functions in people who have had this disease with HRRI.

methodsIn this prospective and observational study, patients proven to have had COVID by molecular methods (polymerase chain reaction positivity) and healthy controls were examined. Electrocardiogram, Transthoracic Echocardiography, Hemogram and Biochemistry tests, and exercise stress test were performed in both groups. HRRIs were calculated by subtracting heart rates at the 1

resultsStudy group (n=30) (Female/Male; n=15/15; mean age=39.8±13.3 years; median body mass index=25.9 kg/m

conclusionAccording to the results of our study, HRRI is impaired as an indicator of autonomic dysfunction in people who have had COVID-19. This situation correlates with other studies that have results of ANS dysfunction due to COVID-19, and this may pose a risk factor for increased mortality and morbidity.

Indexed as

Autonomic nervous systemCOVID-19Heart Rate Recovery Indexmortalityparasympathetic nervous systemsympathetic nervous system

Identifiers

PMID42516795
PMCPMC13402899

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