ArticleJournal of dental research, dental clinics, dental prospects2026
Effect of Resin, Calcium Silicate, and Silicone-Based Root Canal Sealers on Postoperative Pain: A Randomized Controlled Clinical Trial.
Article in Journal of dental research, dental clinics, dental prospects, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: This study aimed to compare the effects of resin- (AH Plus), calcium silicate- (iRoot SP), and silicone-based (GuttaFlow Bioseal) root canal sealers on postoperative pain. Methods: This study included 84 patients with mandibular molars diagnosed with irreversible pulpitis. Root canal shaping procedures were completed using X-Smart Plus (Dentsply Maillefer, Ballaigues, Switzerland) endodontic motor and EndoArt (İnci Dental, İstanbul, Turkey) nickel-titanium rotary system up to #25 (30.06) shaping file for mesial root anals and #30 (0.6) shaping file for root distal canals. The patients were randomly divided into 3 groups based on the root canal sealer used (n=28): group 1: AH Plus, group 2: iRoot SP, and group 3: GuttaFlow Bioseal. Pain scores were recorded using a visual analog scale (VAS) before and after treatment at the 6th, 24th, 48th, and 72nd hours, and at the first week. Additionally, the frequency and timing of analgesic intake were recorded. The chi-squared test was used for categorical variables. The Kruskal-Wallis test was used to compare differences in non-normally distributed continuous data between groups. The Friedman test was used to compare pain scores over time within each group, and the Cochran's Q test was used to analyze analgesic use. Results: No statistically significant differences in median VAS scores were found at various time intervals between the groups ( Conclusion: Resin-, bioceramic-, or silicone-based sealers showed similar effects on postoperative pain.
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