ArticleBiochemistry research international2026
Biological Evaluation and Molecular Docking Study of Ferrociphenol as an Antimelanogenic Agent.
Article in Biochemistry research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Biological Evaluation and Molecular Docking Study of Ferrociphenol as an Antimelanogenic Agent.Biochemistry research international · 2026Article
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10 authors.
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Abstract
Cutaneous hyperpigmentation disorders are associated with abnormal accumulation of melanin pigments, which can be treated using depigmenting agents. In the present study, we investigated the effect of ferrociphenol (Fc-diOH), an organometallic intermediate used in the synthesis of hydroxy-ferrocifen derivatives and previously reported as a tyrosinase inhibitor, on melanogenesis in B16F10 melanoma cells. Cell viability, melanin content, and tyrosinase activity assays demonstrated that treatment with Fc-diOH significantly reduced intracellular melanin levels and tyrosinase activity by 32% and 25%, respectively, in B16F10 cells at 25 nM without inducing significant cytoxicity. Furthermore, the antimelanogenesis activity of Fc-diOH was confirmed in vivo using zebrafish (
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