Evidence map›Paper›PMID 42516537›Full record

ArticleInternational journal of exercise science2026

Moderate Vigorous Physical Activity for Mental Health in Sedentary Middle-Aged Adults.

Elizabeth Moxley, Shaine Henert, Desale Habtezgi, Barrie P Bode, Rachel Kowal, Sara Budhwani, Kris Varothai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of exercise science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth MoxleySchool of Nursing, Northern Illinois University, DeKalb, IL, USA.
Shaine HenertDepartment of Kinesiology, Northern Illinois University, DeKalb, IL, USA.
Desale HabtezgiApplied Mathematics and Applied Statistics, DePaul University, Chicago, IL USA.
Barrie P BodeDepartment of Biological Sciences, Northern Illinois University, DeKalb, IL, USA.
Rachel KowalDepartment of Kinesiology, Northern Illinois University, DeKalb, IL, USA.
Sara BudhwaniSchool of Nursing, Northern Illinois University, DeKalb, IL, USA.
Kris VarothaiApplied Mathematics and Applied Statistics, DePaul University, Chicago, IL USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety and depression affect 32.3% of United States' adults. Guideline-based moderate-to-vigorous intensity physical activity (MVPA) enhances mental health by increasing brain-derived neurotrophic factor (BDNF) and an array of neuroendocrine factors that also mitigate cardiovascular disease (CVD) risk. We examined the response of 14 variables, including depression (Beck Depression Inventory-II), anxiety (Beck Anxiety Inventory), resilience (Connor-Davidson Resilience Scale [CD-RISC]), serum BDNF, and associated CVD risk factors (e.g., HbA1c, body composition, waist circumference) in sedentary middle-aged adults (n=29, M

Indexed as

anxietybrain-derived neurotrophic factorCardiovascular systemdepressionexercise

Identifiers

PMID42516537
PMCPMC13403916

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.