Evidence map›Paper›PMID 42516362›Full record

ArticleFrontiers in dental medicine2026

Keratin-based protection of enamel against acid-erosion.

Simran Mistry, Prema Sukumaran, Sherif Elsharkawy

Abstract read
In one paragraph

Article in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Simran MistryCentre for Clinical, Translational and Oral Sciences, Faculty of Dentistry, Oral and Clinical Sciences, King's College London, London, United Kingdom.
Prema SukumaranCentre for Clinical, Translational and Oral Sciences, Faculty of Dentistry, Oral and Clinical Sciences, King's College London, London, United Kingdom.
Sherif ElsharkawyCentre for Clinical, Translational and Oral Sciences, Faculty of Dentistry, Oral and Clinical Sciences, King's College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enamel erosion is a prevalent and growing oral health concern, affecting approximately 20%-45% of the adult population, with incidence expected to increase. Current preventative strategies rely predominantly on fluoride-based interventions, which, while effective, are not without limitations, particularly in the context of erosive challenges. Consequently, there is an increasing interest in alternative or adjunctive approaches for protecting enamel against acid-induced damage. This study investigated the protective potential of a keratin-based surface treatment against acid-induced enamel erosion and compared its performance with sodium fluoride at clinically relevant concentrations. Enamel specimens from extracted human molars were treated with keratin, sodium fluoride (1,450, 5,000, or 22,600 ppm), artificial saliva, or deionised water, and subsequently exposed to citric or hydrochloric acid under

Indexed as

dental enamelerosionfluoridekeratinmicrohardnesssurface profilometry

Identifiers

PMID42516362
PMCPMC13402517

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.