Evidence map›Paper›PMID 42516326›Full record

ArticleOman journal of ophthalmology

Evaluation of optical coherence tomography in patients with coronary artery disease and systemic hypertension.

Shikha Bhardwaj, Farhat Abrar

Abstract read
In one paragraph

Article in Oman journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shikha BhardwajDepartment of Ophthalmology, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.
Farhat AbrarDepartment of Ophthalmology, Subharti Medical College, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystemic hypertension and coronary artery disease (CAD) cause widespread vascular and neurodegenerative changes, including in the retina. Optical coherence tomography (OCT) offers a noninvasive means to visualise these changes, serving as a potential marker of systemic vascular health. Retinal layers like the peripapillary retinal nerve fiber layer (p-RNFL) and ganglion cell-inner plexiform layer (GC-IPL) are especially vulnerable to vascular damage, making them useful indicators of cardiovascular risk. This study aimed to evaluate and compare the p-RNFL and GC-IPL thickness among hypertensive individuals with and without CAD and healthy controls. MATERIALS AND

methodsThis prospective observational study included 140 participants divided into three groups: healthy controls (Group A,

resultsBoth p-RNFL and GC-IPL were significantly thinned in hypertensive subjects, especially those with CAD. Group A had the highest mean RNFL (114.11 ± 10.09 μm) and GC-IPL (85.07 ± 2.30 μm), whereas Group C showed the lowest (RNFL: 84.90 ± 11.81 μm; GC-IPL: 105.97 ± 11.72 μm). Differences were significant (

conclusionOCT can find early signs of retinal nerve damage related to high blood pressure and CAD, indicating it can be a helpful noninvasive method for checking and tracking heart health risks.

Indexed as

Cardiovascular riskcoronary artery diseaseganglion cell layerhypertensionoptical coherence tomographyretinal biomarkerretinal nerve fiber layer

Identifiers

PMID42516326
PMCPMC13404916

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.