ArticleCase reports in immunology2026
BCG-Related Immune Reconstitution Inflammatory Syndrome and Delayed Donor Chimerism After Allogeneic HSCT in T
Article in Case reports in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- BCG-Related Immune Reconstitution Inflammatory Syndrome and Delayed Donor Chimerism After Allogeneic HSCT in TCase reports in immunology · 2026Article
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8 authors.
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Abstract
Background: Severe combined immunodeficiency (SCID) is a life-threatening disorder that requires early hematopoietic stem cell transplantation (HSCT). In regions where Bacillus Calmette-Guérin (BCG) vaccination is routinely administered at birth, disseminated BCG disease significantly complicates the clinical course in infants. Post-HSCT, immune reconstitution inflammatory syndrome (IRIS) poses an additional challenge, particularly in patients with active mycobacterial infections and mixed chimerism. Case Presentation: We describe a female infant with T Conclusion: This case highlights the diagnostic and therapeutic dilemmas in managing SCID patients with BCG disease after HSCT. Early negative chimerism does not always predict graft failure, and paradoxical IRIS should be considered when clinical deterioration coincides with immune recovery after HSCT. Our findings suggest that conservative corticosteroid-sparing management with intensified antimycobacterial therapy may improve outcomes.
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