ArticleFrontiers in psychology2026
Cortical processing modulation in DOC by preferred music-coupled 40 Hz binaural stimulation: an exploratory EEG-fNIRS study.
Article in Frontiers in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To determine if 40 Hz binaural beat therapy (BBT) combined with preferred music enhances neural complexity and connectivity in disorders of consciousness (DOC). Methods: In a randomized controlled trial, 40 patients with DOC, including minimally conscious state (MCS) and vegetative state/unresponsive wakefulness syndrome (VS/UWS), received either daily 40 Hz BBT with preferred music ( Results: Both groups showed CRS-R improvements ( Conclusion: The findings suggest that 40 Hz BBT combined with preferred music may enhance neural complexity and functional connectivity in patients with DOC, though these effects were not observed in VS/UWS patients receiving the 40 Hz BBT music therapy. Clinical trial registration: https://www.chictr.org.cn/, identifier ChiCTR2300079310.
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