ArticleFrontiers in oncology2026
CD19-negative non-IgM type lymphoplasmacytic lymphoma: a case report and literature review.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Lymphoplasmacytic lymphoma (LPL) that does not fulfill the diagnostic criteria for Waldenström's macroglobulinemia (WM), termed non-IgM type LPL, represents a rare entity that poses significant diagnostic challenges. Here, we report a rare case of CD19-negative non-IgM type LPL. A 69-year-old man was incidentally found to have elevated M-protein and globulin levels during a routine health examination. Subsequent evaluation revealed elevated serum IgG, an IgG-λ monoclonal protein, and markedly elevated urinary λ free light chains. Bone marrow biopsy demonstrated normocellular marrow with approximately 40% cellularity. Immunohistochemistry revealed that CD20
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