Evidence map›Paper›PMID 42515720›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Imidazole-Functionalized Thieno[3,2-c]Quinoline Hybrids in Aggressive Medullary Thyroid Cancer Cell Models: Biological Evaluation and in Silico Insights.

Gabriele La Monica, Alessia Bono, Federica Alamia, Dennis Tocco, Giuseppe Pizzolanti, Antonino Lauria, Annamaria Martorana

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriele La MonicaDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche "STEBICEF", University of Palermo, 90123 Palermo, Italy.ORCID 0000-0001-6510-1943
Alessia BonoDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche "STEBICEF", University of Palermo, 90123 Palermo, Italy.ORCID 0000-0002-9283-4920
Federica AlamiaDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche "STEBICEF", University of Palermo, 90123 Palermo, Italy.ORCID 0009-0004-8281-3511
Dennis ToccoDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche "STEBICEF", University of Palermo, 90123 Palermo, Italy.ORCID 0009-0002-1930-1754
Giuseppe PizzolantiDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-6052-8438
Antonino LauriaDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche "STEBICEF", University of Palermo, 90123 Palermo, Italy.ORCID 0000-0002-5116-6815
Annamaria MartoranaDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche "STEBICEF", University of Palermo, 90123 Palermo, Italy.ORCID 0000-0002-9560-1882

Funding

University of Palermo PJ_GEST_FFR_2025
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antiproliferative activityimidazole hybridsin silico analysismedullary thyroid cancermolecular dockingmolecular dynamics simulationsMZ-CRC-1thienoquinolineTT

Identifiers

PMID42515720
PMCPMC13415440

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.