Evidence map›Paper›PMID 42515717›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Entinostat Enhances Antigen-Specific CD8 T-Cell Response to Immunotherapies in Lung Cancer Models.

Esti Porush, Johnathan Arnon, Baruch Pinchover, Esther Stern, Oz M Shapira, Didier Jean, Galia Blum, Evalyn Yakobovich, Hanna Wald, Amnon Peled and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Esti PorushGene Therapy Institute, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Johnathan ArnonMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 10117 Berlin, Germany.ORCID 0000-0002-5688-5712
Baruch PinchoverGene Therapy Institute, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Esther SternGene Therapy Institute, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Oz M ShapiraDepartment of General Thoracic Surgery, Division of Cardiothoracic Surgery, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Didier JeanINSERM, Université Paris Cité, Sorbonne Université, Centre de Recherche des Cordeliers, F-75006 Paris, France.ORCID 0000-0001-5823-7404
Galia BlumThe Institute for Drug Research, The School of Pharmacy, The Faculty of Medicine, The Hebrew University, Jerusalem 9112102, Israel.ORCID 0000-0002-9374-2489
Evalyn YakobovichThe Institute for Drug Research, The School of Pharmacy, The Faculty of Medicine, The Hebrew University, Jerusalem 9112102, Israel.
Hanna WaldGene Therapy Institute, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Amnon PeledGene Therapy Institute, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.ORCID 0009-0006-4973-2829
Zhangmang WangMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 10117 Berlin, Germany.
Elmehdi BelbarakaMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 10117 Berlin, Germany.
Christian FrieseInstitute of Cancer Immunology, Charité Universitätsmedizin Campus Buch, 13125 Berlin, Germany.
Thomas BlankensteinMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 10117 Berlin, Germany.
Thomas KammertoensMax Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 10117 Berlin, Germany.ORCID 0000-0003-3309-5141
Ori WaldGene Therapy Institute, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.

Funding

Hadassah France donation not applicableIsrael Cancer Association 20240164 and 20251130
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

entinostatHDAC inhibitionimmune checkpoint inhibitorsKRASnon-small cell lung cancerTCR-engineered T cells

Identifiers

PMID42515717
PMCPMC13416286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.