Evidence map›Paper›PMID 42515648›Full record

ReviewViruses2026

The Dicistronic Nature of Picornavirus Genomes? Diverse Translation Mechanisms Enable the Expression of Accessory Proteins from Alternate Open Reading Frames.

Christopher U T Hellen

Abstract readReview
In one paragraph

Review in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Christopher U T HellenDepartment of Cell Biology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203, USA.ORCID 0000-0002-3982-2090

Funding

IRES-mediated initiation of picornavirus translationR21AI188505 · NIAID · SUNY DOWNSTATE MEDICAL CENTER · PI CHRISTOPHER Ulrich Tristram HELLEN · 2025 to 2026
$441k
NIAID NIH HHS R21 AI188505NIH HHS 1R21AI188505-02
6 · The paper itself

Abstract

Members of the

Indexed as

Genome, ViralOpen Reading FramesPicornaviralesPicornaviridaeProtein BiosynthesisViral Regulatory and Accessory Proteins5' Untranslated RegionsGene Expression Regulation, ViralInternal Ribosome Entry SitesRNA, ViralViral Proteins5' Untranslated RegionsInternal Ribosome Entry SitesRNA, ViralViral ProteinsViral Regulatory and Accessory ProteinsIRESpicornavirusprogrammed ribosomal frame-shiftingribosomal scanningtermination–reinitiationtranslation initiation

Identifiers

PMID42515648
PMCPMC13431491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.