Evidence map›Paper›PMID 42515616›Full record

ArticleViruses2026

Highly Pathogenic Avian Influenza H5N1 in South America, 2022-2025: Spread, Affected Species, and Southward Expansion into the Antarctic Region.

Fernanda Sánchez-Rodríguez, Constanza Diaz-Gavidia, Soledad Ruíz, Pedro Jimenez-Bluhm

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fernanda Sánchez-RodríguezOne Health Institute & PhD Program in Conservation Medicine, Faculty of Life Sciences, Universidad Andres Bello, Santiago 8370251, Chile.ORCID 0009-0004-6117-6576
Constanza Diaz-GavidiaEscuela de Medicina Veterinaria, Facultad de Medicina, Facultad de Ciencias Biológicas y Facultad de Agronomía y Sistemas Naturales, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
Soledad RuízEscuela de Medicina Veterinaria, Facultad de Recursos Naturales y Medicina Veterinaria, Universidad Santo Tomás, Santiago 8370003, Chile.
Pedro Jimenez-BluhmEscuela de Medicina Veterinaria, Facultad de Medicina, Facultad de Ciencias Biológicas y Facultad de Agronomía y Sistemas Naturales, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00016 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WEBBY, RICHARD · 2021 to 2025
$91.4M
Agencia Nacional de Investigación y Desarrollo 21260283Agencia Nacional de Investigación y Desarrollo CIN250062Fondo Nacional de Desarrollo Científico y Tecnológico 11251216Fondo Nacional de Desarrollo Científico y Tecnológico 1241662NIH HHS 75N93021C00016ODCDC CDC HHS 75N93021C00016
6 · The paper itself

Abstract

The H5N1 highly pathogenic avian influenza (HPAI) virus has caused severe global losses, reaching South America in 2022 and Antarctica in 2024. Here, we synthesize outbreak reports submitted to the World Organization for Animal Health by South American countries and overseas territories in this continent, and document the virus's unprecedented expansion into Antarctica, affecting wild birds, wild mammals, and domestic poultry. Phylogenetic and time-calibrated Bayesian analyses were performed on available genomic sequences. Over 6 million domestic birds were lost, mostly from commercial operations. Of the 11 South American countries and overseas territories that reported H5N1 to WOAH, 10 reported infections in wild birds, spanning 104 species, 59.62% of which are migratory and predominantly non-trans-equatorial. Marine mammal outbreaks followed wild bird detections, with the South American sea lion (

Indexed as

Influenza A Virus, H5N1 SubtypeInfluenza in BirdsAnimalsAnimals, WildAntarctic RegionsBayes TheoremBirdsDisease OutbreaksPhylogenyPoultrySouth AmericaAntarcticH5N1highly pathogenic avian influenza (HPAI)marine mammalphylogenypoultrySouth Americawild bird

Identifiers

PMID42515616
PMCPMC13431583

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.