Evidence map›Paper›PMID 42515576›Full record

ArticleViruses2026

ConvMut: Exploration of Viral Convergent Mutations Along Phylogenies.

Tommaso Alfonsi, Anna Bernasconi, Emma Fanfoni, Cesare Ernesto Maria Gruber, Fabrizio Maggi, Daniele Focosi

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Life (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tommaso AlfonsiDepartment of Electronics, Information, and Bioengineering, Politecnico di Milano, 20133 Milan, Italy.ORCID 0000-0002-4707-8425
Anna BernasconiDepartment of Electronics, Information, and Bioengineering, Politecnico di Milano, 20133 Milan, Italy.ORCID 0000-0001-8016-5750
Emma FanfoniDepartment of Electronics, Information, and Bioengineering, Politecnico di Milano, 20133 Milan, Italy.
Cesare Ernesto Maria GruberLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0002-8831-3380
Fabrizio MaggiLaboratory of Virology and Laboratories of Biosecurity, National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, 00149 Rome, Italy.ORCID 0000-0001-7489-5271
Daniele FocosiNorth-Western Tuscany Blood Bank, Pisa University Hospital, 56126 Pisa, Italy.ORCID 0000-0001-8811-195X

Funding

Italian Ministry of University and Research P2022CNN2
6 · The paper itself

Abstract

Convergent evolution in protein antigens is common across pathogens, including SARS-CoV-2; the most likely reason is the need to evade the selective pressure exerted by previous infection- or vaccine-elicited immunity. There is a pressing need for automated analysis of convergent mutations. We developed ConvMut, a tool to identify patterns of recurrent mutations in SARS-CoV-2 evolution; we exploited the granular phylogeny-based lineage hierarchy developed by PANGO, allowing us to observe

Indexed as

Evolution, MolecularMutationPhylogenySARS-CoV-2Amino Acid SubstitutionCOVID-19HumansSpike Glycoprotein, CoronavirusSpike Glycoprotein, Coronavirusconvergent evolutionconvergent mutationsgenomic surveillanceSARS-CoV-2viral evolution

Identifiers

PMID42515576
PMCPMC13431514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.