Evidence map›Paper›PMID 42515564›Full record

ArticleViruses2026

The Effect of Highly Virulent PRRSV-2 (L1C.5) Infection on Calcium Homeostasis and Bone Changes in Pigs Fed with Various Levels of Dietary Vitamin D.

Panchan Sitthicharoenchai, Kelly Grace Keen, Veeraya Bamrung, Chareerut Phruksaniyom, Sara Hough, Eric van Heugten, Devorah Stowe, Jianqiang Zhang, Michael C Rahe

Abstract read
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In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Panchan SitthicharoenchaiDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0000-0002-4412-7121
Kelly Grace KeenDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Veeraya BamrungDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Chareerut PhruksaniyomDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Sara Houghdsm-firmenich, Plainsboro, NJ 08536, USA.
Eric van HeugtenDepartment of Animal Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0000-0002-6982-1136
Devorah StoweDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.
Jianqiang ZhangDepartment of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0001-7228-6202
Michael C RaheDepartment of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0000-0003-2123-4124

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is a major cause of disease in swine production, resulting in a high economic impact that has been exacerbated by the recent North American outbreaks of highly virulent PRRSV-2 strain (L1C.5). However, there is limited knowledge about how underlying systemic infections, particularly with this emergent PRRSV strain, affect calcium regulation and bone in pigs fed varying levels of vitamin D. To address this, the goal of this study was to determine the effect of different dietary vitamin D levels and PRRSV infection on calcium regulation and phenotypic changes in bone. Three-week-old pigs (

Indexed as

Bone and BonesCalciumHomeostasisPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusVitamin DAnimal FeedAnimalsDietDietary SupplementsSwineCalciumVitamin Dbone marrowmyelonecrosisPRRSVswinevitamin D

Identifiers

PMID42515564
PMCPMC13431496

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.