Novel Electrochemical Aptasensor Based on Iron-Cobalt-Doped Magnetic Carbon and cDNA-Polyacrylic Acid for the Determination of Aflatoxin B1 in Peanuts.

Zhongyu Li, Zili Xia, Dongdong Chen, Yang Han, Heng Zhang, Xia Sun, Wenping Zhao

Abstract read

In one paragraph

Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhongyu LiSchool of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China.

Zili XiaSchool of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China.

Dongdong ChenSchool of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China.

Yang HanSchool of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China.

Heng ZhangSchool of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China.

Xia SunSchool of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China.

Wenping ZhaoSchool of Agricultural Engineering and Food Science, Shandong University of Technology, No. 266 Xincun Xilu, Zibo 255049, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of aflatoxin B1 (AFB1) is ubiquitous in the environment, and it is considered one of the most powerful natural carcinogenic substances. In this study, a highly sensitive electrochemical aptasensor was designed to detect aflatoxin B1 (AFB1) in peanuts. Iron-cobalt-doped magnetic carbon (Fe-Co/NPC) was used to enhance the conductivity of the electrode and catalytic performance, providing an increased specific surface area. Gold nanoparticles (AuNPs) were used to immobilize an aptamer. And cDNA-polyacrylic acid (cDNA-PAA) nanogels served as a high-density carrier for cDNA and an active signal amplification unit, significantly increasing the charge transfer resistance (Rct) through steric hindrance and electrostatic repulsion. Unlike traditional aptasensors that relied on passive blocking agents, we designed a competitive displacement mechanism. AFB1 competed with cDNA-PAA during detection in order to bind to the aptamer, which resulted in the removal of the non-conductive complex and a substantial increase in the electrochemical signal. Under the optimal conditions, the aptasensor had a linear response range of 1-1000 ng/L and a limit of detection (LOD) of 0.3 ng/L. It displayed high specificity, reproducibility, and stability. In spiked peanut samples, the recoveries ranged from 98.04% to 100.86%. Due to its sensitivity and reliability, this aptasensor has a great determination of AFB1 in food safety applications.

Indexed as

Aflatoxin B1Aptamers, NucleotideArachisBiosensing TechniquesDNA, ComplementaryElectrochemical TechniquesAcrylic ResinsCarbonCobaltGoldIronLimit of DetectionMetal NanoparticlesAcrylic ResinsAflatoxin B1Aptamers, NucleotideCarboncarbopol 940CobaltDNA, ComplementaryGoldIronaflatoxin B1electrochemical aptasensorpeanutpolyacrylic acidrapid determination

Identifiers

PMID42515233

DOI10.3390/s26144348

PMCPMC13419315

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.