Evidence map›Paper›PMID 42515206›Full record

ArticleToxics2026

Uncovering Urinary Neonicotinoid Exposure Signatures Among Older Adults in South China: A Multicenter Biomonitoring Study.

Xiaoxiao Chen, Chiqun Shan, Yiming Ge, Yuli Lin, Bo Fu, Canrong Zheng, Yuhua Huang, Shaoyou Lu

Abstract read
In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoxiao ChenChaozhou People's Hospital, Chaozhou Hospital Affiliated to Shantou University Medical College, Chaozhou 521011, China.
Chiqun ShanResearch Center for Environment and Health, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Yiming GeResearch Center for Environment and Health, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Yuli LinResearch Center for Environment and Health, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Bo FuResearch Center for Environment and Health, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.
Canrong ZhengChaozhou People's Hospital, Chaozhou Hospital Affiliated to Shantou University Medical College, Chaozhou 521011, China.
Yuhua HuangChaozhou People's Hospital, Chaozhou Hospital Affiliated to Shantou University Medical College, Chaozhou 521011, China.
Shaoyou LuResearch Center for Environment and Health, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, China.

Funding

National Natural Science Foundation of China No. 42277424National Natural Science Foundation of China No. 42477296Shenzhen Science and Technology Program No. JCYJ20230807110903008Shenzhen Science and Technology Program No. JCYJ20240813150902004
6 · The paper itself

Abstract

Neonicotinoid insecticides (NEOs) are widely used neuroactive pesticides, but biomonitoring evidence among older adults remains limited. This multicenter cross-sectional study characterized urinary exposure profiles of NEOs and their metabolites among 419 older adults from South China. Ten urinary NEO biomarkers, including six parent compounds and four metabolites, were measured using high-performance liquid chromatography coupled with tandem mass spectrometry. NEOs were frequently detected in urine samples; except for thiacloprid and acetamiprid, with detection frequencies of 81.67% and 65.48%, respectively, all other compounds were detected in more than 90% of participants. Among the parent NEOs, clothianidin had the highest median concentration (1.402 μg/L), followed by dinotefuran (1.240 μg/L) and thiamethoxam (0.888 μg/L). The main metabolite was

Indexed as

biomonitoringneonicotinoidsolder adultsSouth Chinaurinary biomarkers

Identifiers

PMID42515206
PMCPMC13418382

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.