Photodegradation of Buspirone: Ecotoxicological Assessment and Identification of Photoproducts.

Grzegorz Nałęcz-Jawecki, Marta Kozak, Joanna Giebułtowicz, Milena Wawryniuk, Agata Drobniewska

Abstract read

In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Grzegorz Nałęcz-JaweckiDepartment of Toxicology and Food Science, Medical University of Warsaw, Banacha 1 Str., 02-097 Warszawa, Poland.ORCID 0000-0003-4945-3687

Marta KozakDepartment of Toxicology and Food Science, Medical University of Warsaw, Banacha 1 Str., 02-097 Warszawa, Poland.

Joanna GiebułtowiczDepartment of Drug Chemistry, Pharmaceutical and Biomedical Analysis, Medical University of Warsaw, Banacha 1 Str., 02-097 Warszawa, Poland.ORCID 0000-0002-2567-4453

Milena WawryniukDepartment of Toxicology and Food Science, Medical University of Warsaw, Banacha 1 Str., 02-097 Warszawa, Poland.

Agata DrobniewskaDepartment of Toxicology and Food Science, Medical University of Warsaw, Banacha 1 Str., 02-097 Warszawa, Poland.ORCID 0000-0001-8320-1200

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buspirone is an anxiolytic drug used for the treatment of generalized anxiety disorder. Even though it was patented 50 years ago, it is still among the top three most commonly prescribed anti-anxiety medications in the US. Its fate in the environment and ecotoxic effects have not yet been assessed. In this study, the direct and indirect (with humic acids) photodegradation of buspirone was assessed using the SunTest CPS+ sunlight simulator in two radiation ranges: 280-800 nm and 290-800 nm. The concentration of buspirone and the formation of photoproducts were assessed using liquid chromatography with a diode array and mass spectrometry detector. Toxicity was assessed using biotests with luminescent bacteria and protozoan

Indexed as

ecotoxicologypharmaceuticals in the environmentrisk assessment

Identifiers

PMID42515198

DOI10.3390/toxics14070633

PMCPMC13419151

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.