Evidence map›Paper›PMID 42515110›Full record

ReviewToxics2026

Applications of Stem Cells and Modern Toxicological Analytical Methods in the Toxicity of Microplastics.

Mohan Wang, Dilixiati Wubuli, Mulati Julaiti, Pengfei Huang, Jinghui Xie, Bowen Hu

Abstract readReview
In one paragraph

Review in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohan WangState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830017, China.
Dilixiati WubuliPhysiology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830017, China.
Mulati JulaitiState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830017, China.
Pengfei HuangState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830017, China.
Jinghui XieState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830017, China.
Bowen HuState Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi 830017, China.

Funding

National Natural Science Foundation of China 22206162Science and Technology Department of Xinjiang Uyghur Autonomous Region 03010507Science and Technology Department of Xinjiang Uyghur Autonomous Region 2022D01C711
6 · The paper itself

Abstract

Microplastics (MPs) are an emerging environmental pollutant, and their contamination has emerged as a pressing global environmental concern. Developmental processes exhibit heightened sensitivity to environmental perturbations, and MP exposure can induce long-term adverse effects on organismal health by disrupting fundamental cellular processes. This review focuses on the toxicity and developmental toxicity risks of microplastics investigated using stem cell models. The core section comprehensively summarizes the primary mechanisms through which MP exposure interferes with the biological functions of stem cells, including the impairment of self-renewal capacity and lineage specification, as well as the inhibition of tissue-specific differentiation and organogenesis. Finally, the integration and application of modern toxicological methods in deepening research and improving risk assessment capabilities are synthesized. This review aims to provide a systematic perspective to understand the developmental hazards of MPs and look forward to future risk studies based on stem cell modeling, providing theoretical basis and fundamental support.

Indexed as

developmental toxicitymicroplasticsstem cell modelstoxicological approaches

Identifiers

PMID42515110
PMCPMC13417448

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.